66 Results for "

Erythrina stricta Roxb.

" in MedChemExpress (MCE) Product Catalog:
Products (66)

66 Results for "Erythrina stricta Roxb." in MCE Product Catalog:

9
9 Publications Verification
Referencia número: HY-N0436
No. CAS: 572-31-6
Engeletin is a flavanonol glycoside isolated from Smilax glabra Roxb. , inhibits NF-κB signaling-pathway activation, and possesses anti-inflammatory, analgesic, diuresis, detumescence, and antibiosis effects.
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4
4 Cited Publications
Referencia número: HY-N0498
No. CAS: 13063-04-2
Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway, also has anti-inflammatory activity. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway .
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2
2 Cited Publications
Referencia número: HY-N1073
No. CAS: 51225-30-0
Synonyms: 6-Isopentenylgenistein; Erythrinin B
Wighteone (6-Isopentenylgenistein; Erythrinin B) is a prenylated isoflavone that acts as a HSP90/EGFR L858R/T790M inhibitor and antifungal agent. Wighteone reduces the expression level of HSP90, blocks EGF-induced phosphorylation of EGFR, and thereby inhibits the downstream ERK and AKT signaling pathways. Wighteone induces cell cycle redistribution, inhibits proliferation and triggers apoptosis in cancer cells. Wighteone can be isolated from Erythrina suberosa, and can also be induced to synthesize in Lotus japonicus under specific conditions. Wighteone can be used to study HER2-positive breast cancer, leukemia, non-small cell lung cancer with EGFR L858R/T790M mutation, and fungal infections .
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1
1 Cited Publications
Referencia número: HY-107670
No. CAS: 29734-68-7
Pureza:  98.85%
Synonyms: DHβE hydrobromide
Dihydro-β-erythroidine (DHβE) hydrobromide is a potent, orally active, and competitive antagonist of neuronal nAChRs. Dihydro-β-erythroidine hydrobromide shows selectivity for α4β4 and α4β2 nAChRs, with IC50s of 0.19 and 0.37 μM, respectively. Antidepressant-like activities .
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1
1 Cited Publications
Referencia número: HY-N2661
No. CAS: 1570-09-8
5,7-Dihydroxy-3,4',8-trimethoxyflavone (Substance E) can be isolated from Conyza stricta Willd .
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1
1 Cited Publications
Referencia número: HY-N3857
No. CAS: 63807-85-2
Erythrinin C is an isoflavones that can be isolated from Erythrina suberosa var .
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Referencia número: HY-N1163
No. CAS: 6474-90-4
Synonyms: (-)-Tetrahydroalstonine
Tetrahydroalstonine ((-)-Tetrahydroalstonine) is an indole alkaloid and a selective α₂-adrenergic receptor antagonist. Tetrahydroalstonine exhibits certain neuroprotective effects. Tetrahydroalstonine can regulate autophagy-lysosomal function by activating the Akt/mTOR pathway, significantly reducing OGD/R-induced primary cortical neuronal injury .
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Referencia número: HY-W008226
No. CAS: 480-66-0
Synonyms: 2,4,6-trihydroxyacetophenone; 1-(2,4,6-Trihydroxyphenyl)ethanone
Phloracetophenone (2,4,6-trihydroxyacetophenone) is the aglycone part of acetophenone glycoside obtained from Curcuma comosa Roxb, with cholesterol-lowering activity. Phloracetophenone enhances cholesterol 7α-hydroxylase (CYP7A1) activity . Phloracetophenone stimulats bile secretion mediated through Mrp2 .
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Referencia número: HY-N4085
No. CAS: 38950-94-6
Synonyms: 4'-O-Glucosylvitexin
Vitexin 4'-glucoside is a leaf flavonoid identified from Briza stricta .
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Referencia número: HY-N1653
No. CAS: 74161-25-4
2,3-Dehydrokievitone is a isoflavanone found in Erythrina sacleuxii .
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Referencia número: HY-N16516
No. CAS: 146428-62-8
Velutinam is an alkaloid. Velutinam can be isolated from twigs of Uvaria grandiflora Roxb. Velutinam shows antioxidant activity. Velutinam can be used in the research of bacterial infections .
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Referencia número: HY-N16539
No. CAS: 188300-82-5
Jaslanceoside B is a secoiridoid glucoside found in Jasminum lanceolarium Roxb .
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Referencia número: HY-N3484
No. CAS: 478158-77-9
Isoerysenegalensein E (compound 3) is a natural product that can be found in Erythrina lysistemon .
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Referencia número: HY-N2857
No. CAS: 34086-50-5
Alpinumisoflavone (compound 2) is a flavonoid derivative isolated from the stem bark of Erythrina lysistemon Hutch .
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Referencia número: HY-N6032
No. CAS: 60820-94-2
Synonyms: Phytolaccoside B
Esculentoside B (Phytolaccoside B) is a natural product from the roots of Phytolacca acinosa Roxb. Esculentoside B is neurotoxic to zebrafish larvae, and impairs their central nervous system development. Esculentoside B inhibits inflammatory response and has antifungal activity .
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Referencia número: HY-115507
No. CAS: 1332290-68-2
Áreas de investigación:  

Cancer

NMac1 is an orally active Nm23/NDPK activator. NMac1 directly binds to Nm23-H1 and activates the NDPK activity of recombinant Nm23-H1 with an EC50 of 10.7 uM. NMac1 induces AMPK activation and inhibits mTOR and ERK, leading to mitochondrial OXPHOS dysregulation and suppressing mitochondrial ROS production, which in turn induces mitochondrial dysfunction in MDA-MB-231 cells. NMac1 inhibits Complex I activity and suppresses changes in morphology and actin cytoskeleton organization following Rac1 activation in MDA-MB-231 cells. NMac1 inhibits tumor invasion, migration and metastasis. NMac1 is useful for studying metastatic tumors, such as breast cancer. NMac1 can be isolated from the ginger cassumunar Roxb .
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Referencia número: HY-N2906
No. CAS: 119309-02-3
Synonyms: Atalantoflavone
Limonianin (Atalantoflavone) is a flavone, that can be isolated from Erythrina sigmoidea and the root bark of Citrus limonia. Limonianin presents inhibitory effect against P. gingivalis. Limonianin shows cytotoxic activity against multidrug-resistant (MDR) cancer cell lines .
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Referencia número: HY-112657
No. CAS: 30199-26-9
Pureza:  98.46%
Xanthorrhizol, isolated from Curcuma xanthorrhiza Roxb, is a potential antibacterial agent.
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Referencia número: HY-N2634
No. CAS: 164204-79-9
Uvarigranol B, a polyoxygenated cyclohexene, is obtained from the roots of Uvaria grandiflora Roxb (Annonaceae) .
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Referencia número: HY-N8203
No. CAS: 1879030-01-9
4'-Hydroxy-6,7,8,3'-tetramethoxyflavonol is a natural compound that could be found in Getonia floribunda Roxb .
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